Factor IX - Wikipedia
Factor IX (EC 3.4.21.22), also known as Christmas factor, is one of the serine proteases involved in coagulation; it belongs to peptidase family S1. Deficiency of this protein causes haemophilia B. It was discovered in 1952 after a young boy named Stephen Christmas was found to be lacking this exact factor, leading to haemophilia. [5] .
Coagulation Factor IX for Hemophilia B Therapy - PMC
Factor IX is a zymogen enzyme of the blood coagulation cascade. Inherited absence or deficit of the IX functional factor causes bleeding disorder hemophilia B, which requires constant protein replacement therapy.
Factor ix (intravenous route, injection route) - Mayo Clinic
2024年1月31日 · Factor IX is a protein produced naturally in the body. It helps the blood form clots to stop bleeding. Injections of factor IX are used to treat hemophilia B, which is sometimes called Christmas disease.
Hemophilia B - National Bleeding Disorders Foundation
Hemophilia B, also called factor IX (FIX) deficiency or Christmas disease, is a genetic disorder caused by missing or defective factor IX, a clotting protein. Although it is passed down from parents to children, about 1/3 of cases are caused by a …
Blood coagulation factor IX: structural insights impacting ...
2024年11月21日 · Coagulation factor IX plays a central role in hemostasis through interaction with factor VIIIa to form a factor X–activating complex at the site of injury. The absence of factor IX activity results in the bleeding disorder hemophilia B.
Factor IX - an overview | ScienceDirect Topics
Factor IX is a vitamin K-dependent zymogen that, when absent or deficient, results in a bleeding disorder called hemophilia B. It is activated by either factor XIa/Ca++ or factor VIIa/tissue factor/Ca++ and functions as a serine protease in the coagulation cascade, converting factor X …
Factor IX - (Anatomy and Physiology I) - Fiveable
Factor IX, also known as Christmas factor, is a blood coagulation protein that plays a crucial role in the intrinsic pathway of the coagulation cascade. It is an essential component in the process of hemostasis, the body's natural mechanism to stop bleeding and promote blood clot formation.
- 某些结果已被删除