Immunohistochemical and molecular study for differential …
At 24 hr, postmortem changes were recorded in brain tissue, represented by the pyknotic nucleus of neurons and vacuolation of brain parenchyma. Besides, lung tissues exhibited collapse as well as the destruction of vascular, bronchial, and alveolar walls. At 48, the brain is exposed to shrunken neurons with dark cytoplasm and pyknotic nucleus.
Treatment of the lung injury of drowning: a systematic review
2021年7月19日 · Drowning is a cause of significant global mortality. The mechanism of injury involves inhalation of water, lung injury and hypoxia. This systematic review addressed the following question: In drowning patients with lung injury, what is the evidence from primary studies regarding treatment strategies and subsequent patient outcomes?
There are a group of restrictive lung characterized by increase in inflammatory cells or fibroblasts in the interstitium/alveolar walls. While they can all lead to fibrosis, some diseases do so invariably (UIP) and others less commonly (NSIP, sarcoid, hypersensitivity).
Postmortem Imaging in Drowning - SpringerLink
2019年7月5日 · The next step in the evaluation of the respiratory system is the study of the parenchymal changes observed in drowning. Parenchymal patterns that can be encountered are distinguished into two subcategories: ground-glass opacities and consolidations.
Diagnosing fatal drownings: A review of the postmortem findings
2024年11月1日 · Drowning is considered one of the most challenging causes of death to diagnose in forensic medicine. This complexity arises from the fact that pathophysiological findings are both non-specific and unreliable, making it problematic to distinguish between drowning or postmortem immersion during medico-legal death investigations.
Macroscopical, Microscopical, and Laboratory Findings in Drowning …
Hypoxemia plays a primary role in death by drowning, whereas serum electrolyte changes may be observed in experimental models but have little or no clinical significance in humans.
Hypoxemia seems to be the most severe pathophysiologic consequence of nonfatal drowning. Victims may sustain severe organ damage, mainly to the brain. It is dificult to predict an accurate neurological prognosis from the initial clinical presentation, laboratory and …
Can post-mortem CT reliably distinguish between drowning and …
2014年7月17日 · Certain CT findings can be supportive of the diagnosis of drowning in a body recovered from water, but there is considerable overlap between the CT features of drowning and non-drowning asphyxiation. Post-mortem CT has the advantage of evaluating anatomical areas not visualized in classic autopsy and thus providing additional information to the ...
Diagnosis of drowning using postmortem computed tomography …
Postmortem computed tomography revealed fluid in the paranasal sinuses, airways, stomach, and duodenum; emphysema aquosum; and mosaic pattern of the lung parenchyma. Endoscopic examination additionally detected Paltauf spots. The results were consistent with those of conventional autopsy.
Show pathological feature of salt water drowning in rats, the brain is showing changes represented by death of neurons, and marked vacuolation in the brain parenchyma, heart is showing death of cardiomyocytes and increases in interstitial spaces, lung displays pulmonary atelectasis and over distended alveoli with air with rupture of capillaries ...