Phosphorylcholine-based polymers and their use in the …
2000年10月1日 · This article provides an overview of work carried out on the synthesis and non-fouling properties of phosphorylcholine (PC)-containing polymers. The concept of biomimicry is outlined and the major classes of synthetic PC-based materials described.
Phosphorylcholine-containing polymers for biomedical applications ...
2004年11月10日 · Polymer surfaces with phosphorylcholine groups have properties that resist protein adsorption and cell adhesion. In particular, MPC is one of the best monomers, because it has been prepared with a bioinspired biomembrane structure and can be used to make a wide variety of polymers.
Recent progress and perspectives in applications of 2 ...
Among biocompatible polymers, a polymer family containing 2-methacryloyloxyethyl phosphorylcholine (MPC) has attracted attention for both fundamental studies and applications. 1–6 MPC polymers are synthetic phospholipid polymers with zwitterionic phosphorylcholine (PC) head groups, which can form cell-membrane-like structures on various ...
Phosphorylcholine polymer nanocapsules prolong the circulation …
2016年2月1日 · Through extensive cellular studies, we demonstrate that the crosslinked phosphorylcholine polymer shell effectively prevents the encapsulated protein from being phagocytosed by macrophages, which play an essential …
2-Methacryloyloxyethyl Phosphorylcholine Polymers
2014年5月7日 · The synthesis and properties of phosphorylcholine group-bearing methacrylate, 2-methacryloyloxyethyl phosphorylcholine (MPC), and its polymers are described. Molecular design of the MPC polymers with significant functions for biomedical and medical applications is summarized in detail.
Synthesis and characterisation of phosphorylcholine-based polymers ...
2000年9月1日 · We highlight herein the application of RAFT to the synthesis of water-soluble/dispersible (co)polymers under homogeneous reaction conditions in both aqueous and organic media. Additionally, we review the aqueous solution properties of advanced stimuli–responsive systems with a particular emphasis on …
Phosphorylcholine-based polymers and their use in the
2000年10月1日 · This article provides an overview of work carried out on the synthesis and non-fouling properties of phosphorylcholine (PC)-containing polymers. The concept of biomimicry is outlined and the major classes of synthetic PC-based materials described.
Biomimetic polymers with phosphorylcholine groups as
Polymers with a phosphorylcholine group, a polar group of phospholipid molecules, are particularly interesting. A methacrylate monomer, 2-methacryloyloxyethyl phosphorylcholine (MPC), was developed using efficient synthetic reactions and purification techniques.
The effect of cationically-modified phosphorylcholine polymers …
2017年8月17日 · The effect of introducing cationic charge into phosphorylcholine (PC)-based polymers has been investigated in this study with a view to using these materials as coatings to improve bone formation and osseointegration at the bone-implant interface.
A Study of the Phosphorylcholine Polymer Coating of a ... - MDPI
2023年6月29日 · A phosphorylcholine polymer (poly(MPC–co–BMA–co–TSMA), PMBT) was prepared by free radical polymerization and coated on the surface of the polymethylpentene hollow fiber membrane (PMP–HFM). ATR–FTIR and SEM analyses showed that the PMBT polymer containing phosphorylcholine groups was uniformly coated on the surface of …