Progestogen - Wikipedia
Progestogens, also sometimes written progestins, progestagens or gestagens, [1] are a class of natural or synthetic steroid hormones that bind to and activate the progesterone receptors (PR). [2][3] Progesterone is the major and most important progestogen in the body.
Understanding Progestins: From Basics to Clinical Applicability
Progesterone (P4) is a steroid hormone containing 21 carbons that is synthesized primarily by glands in the ovaries, adrenals, and testicles and plays a fundamental role in coordinating the reproductive physiology of females (ovulation, endometrium transformation, and pregnancy maintenance) [1, 2].
Using Progestins in Clinical Practice | AAFP
2000年10月15日 · Progestational agents have many important functions, including regulation of the menstrual cycle, treatment of dysfunctional uterine bleeding, prevention of endometrial cancer and...
Progestins - StatPearls - NCBI Bookshelf
2024年1月10日 · Progestins, synthetic compounds emulating the action of progesterone, serve a pivotal role in various medical applications, spanning from contraception to postmenopausal hormone replacement therapy.
Progesterone - Wikipedia
Progesterone, produced by the placenta during pregnancy, plays a role in fetal sexual differentiation by serving as a precursor molecule for the synthesis of DHT via the backdoor pathway.
THE UTERUS DURING PROGESTATION: HORMONAL …
1979年1月1日 · Our aim has been to characterize the metabolic activity of the uterus during early progestation and to determine how the ovarian steroid hormones interact to produce a tissue substrate capable of allowing blastocyst implantation.
The selective progesterone receptor modulator-promegestone …
Progesterone, as its name implies, is a progestation hormone that maintains myometrial quiescence for most of pregnancy and blocks labor. It mainly inhibits the expression of genes in myometrial cells, whose products, referred collectively as contraction-associated proteins (CAPs), increase contractility and excitability to produce the labor state.
Progestogen (medication) - Wikipedia
Progestogens are agonists of the progesterone receptors (PRs) and produce progestogenic, or progestational, effects. [1] . They have important effects in the female reproductive system (uterus, cervix, and vagina), the breasts, and the brain. [1] .
Prevention of preterm birth by progestational agents: what are the ...
2016年10月6日 · Clinically, vaginal progesterone (VP) and 17 alpha-hydroxyprogestreone caproate (17P) have been shown to prevent preterm birth (PTB) in high risk populations. We hypothesize treatment with these agents may prevent PTB by altering molecular pathways involved in uterine contractility or cervical remodeling.
Development of the Progestational Uterus: Metabolic Aspects
1975年2月1日 · The relationship displayed in Figure 16 exists to a varying degree during each day from proestrus through Day 5 of progestation: changes in the availability of oxygen and other exogenous substrates affect the rate of utilization of glucose by the cell.
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