Purkinje cell - Wikipedia
Purkinje cells or Purkinje neurons, named for Czech physiologist Jan Evangelista Purkyně who identified them in 1837, [2] are a unique type of prominent large neurons located in the cerebellar cortex of the brain.
Histology, Purkinje Cells - StatPearls - NCBI Bookshelf
2022年11月14日 · Purkinje cells are a unique type of neuron-specific to the cerebellar cortex. They are remarkable (and instantly recognizable) for their massive, intricately branched, flat dendritic trees, which give them the ability to integrate large amounts of information and learn by remodeling their dendrites.
Purkinje cell | Granule cells, Cerebellum & Neurons | Britannica
Purkinje cell, large neuron with many branching extensions that is found in the cortex of the cerebellum of the brain and that plays a fundamental role in controlling motor movement. These cells were first discovered in 1837 by Czech physiologist Jan Evangelista Purkinje.
Purkinje Cell - an overview | ScienceDirect Topics
Purkinje cells are the most morphologically striking cellular elements of the cerebellar cortex. They are arranged in a single row throughout the entire cerebellar cortex between the molecular (outer) layer and the granular (inner) layer.
The Role of Purkinje Cells in Movement and Learning
2023年10月20日 · Nestled within the cerebellum, a region of the brain crucial for motor control and coordination, reside cells known as Purkinje cells. These cells are not only striking for their intricate structure but also for their profound influence on how we move and learn.
Purkinje Cell Representations of Behavior: Diary of a Busy Neuron
As the only output neurons of the cerebellar cortex, Purkinje cells are a key node in the network and, therefore, are integral to understanding cerebellar function. This review focuses on the signals represented in the discharge of Purkinje cells and what those signals tell us about cerebellar function.
Purkinje Cell Patterning—Insights from Single-Cell Sequencing
Despite their homogeneous appearance, Purkinje cells are remarkably diverse with respect to their molecular phenotypes, physiological properties, afferent and efferent connectivity, as well as their vulnerability to insults.
Snapshot: What are Purkinje cells? - National Ataxia Foundation
Purkinje cells are important neuronal cells located in the outer layers of the cerebellum. The cerebellum is part of the brain that is primarily known for controlling sense of balance and movement but can also influence learning, memory, and mood.
Interactions between Purkinje cells and granule cells coordinate …
We propose that the wiring of Purkinje cells for function falls into two developmental phases: an initial phase that is guided by intrinsic mechanisms and a later phase that is guided by dynamically-acting cues, some of which are provided by granule cells.
Purkinje Cell - an overview | ScienceDirect Topics
Purkinje cells are GABAergic neurons and provide the sole output of the cerebellar cortex to the DCN and vestibular nuclei in the brain stem. Purkinje cells receive excitatory input from climbing fibers originating from the inferior olivary nucleus in the brain stem.