人类记忆中的Theta振荡 - 知乎 - 知乎专栏
2021年3月31日 · 在提取阶段阶段，Theta波处于波谷相位时，在长时抑制（long-term depression，LTD）的作用下，大脑皮层的兴奋性被降低，新记忆的形成受到抑制，从而较少的外界刺激信息输入到大脑皮层。. 与此同时，CA1区的细胞活性被CA3区输入的信息激活，同歩激 …
eLife︱北京大学吴思团队报道海马位置细胞形成theta sweeps和相 …
实验上观测到，当老鼠运动时，海马区的神经元集体活动产生的场电位（Local field potential, LFP）会产生4-12hz周期性震荡信号，被称为theta波。早期研究发现，位置细胞只会在特定的theta波的相位发电。这个相位会随着动物穿过该细胞位置场的过程而逐步提前。
Theta sequences are essential for internally generated ... - Nature
2014年12月22日 · How might the theta sequence–based, internally generated firing fields be associated with sensory cues during the formation of the compound firing fields?
Hippocampal place cell sequences differ during correct and ... - Nature
2021年6月7日 · Theta rhythms temporally coordinate sequences of hippocampal place cell ensembles during active behaviors, while sharp wave-ripples coordinate place cell sequences during rest. We...
The role of replay and theta sequences in mediating hippocampal ...
Sequential activity is seen in the hippocampus during multiple network patterns, prominently as replay activity during both awake and sleep sharp-wave ripples (SWRs), and as theta sequences during active exploration.
Theta sequences of place cells during behavior play a role in acquisition of spatial memory, trajectory prediction and decision making. In awake rest and slow wave sleep, place cell sequences occur during the sharp wave-ripples (SWRs), called “replay”, which is crucial for memory consolidation and retrieval.
Theta-phase dependent neuronal coding during sequence learning …
2021年8月10日 · Neuronal firing elicited by different items in a sequence was phase-locked to the theta oscillation at distinct phases, and we observed a gradual phase precession that spanned three items in...
Associative and predictive hippocampal codes support memory …
Previous studies have shown that both theta and replay sequences not only reproduce animal recent experiences but can also construct novel predictive representations. Theta sequences encode trajectories ahead of the animal’s current location and can represent alternative paths at decision points (44–46).
Learning to predict future locations with internally generated theta ...
2023年5月12日 · Decoding the positions represented by the population activity during these theta sequences reveals trajectories that start behind the current position of the animal and sweep ahead [7–14]. Previously, we found that theta sweeps in a population of CA1 place cells vary systematically across the environment [ 15 ].
Coordinated Emergence of Hippocampal Replay and Theta Sequences …
2019年3月4日 · We have also demonstrated the parallel, late, and gradual emergence of theta sequences during development. Theta sequences are ordered sequences of hippocampal place cell firing that are nested within each theta cycle and reproduce, at compressed timescales, the spatial organization of place fields in the environment.