Transaminase - Wikipedia
Transaminases or aminotransferases are enzymes that catalyze a transamination reaction between an amino acid and an α- keto acid. They are important in the synthesis of amino acids, which form proteins. An amino acid contains an amino (NH 2) group. A …
Transaminase - an overview | ScienceDirect Topics
Transaminases, also known as aminotransferases, are a group of enzymes that mediate the transfer of an amine group between an amino acid and a keto acid (Boison, 2007).
A quantum chemical study of the ω-transaminase reaction mechanism …
2015年6月30日 · ω-Transaminases are valuable tools in biocatalysis due to their stereospecificity and their broad substrate range. In the present study, the reaction mechanism of Chromobacterium violaceum ω-transaminase is investigated by means of density functional theory calculations.
Transaminase catalyzed asymmetric synthesis of active …
2024年3月16日 · Transaminases, as catalysts, have emerged as green, efficient, and highly selective solutions for substrates containing ketones or aldehydes, demonstrating exceptional performance in the synthesis of active drug molecules and natural products.
Transaminase - an overview | ScienceDirect Topics
Transamination is the process by which amino groups are removed from amino acids and transferred to acceptor keto-acids to generate the amino acid version of the keto-acid and the keto-acid version of the original amino acid.
Transamination - Wikipedia
Transamination in biochemistry is accomplished by enzymes called transaminases or aminotransferases. α-ketoglutarate acts as the predominant amino-group acceptor and produces glutamate as the new amino acid.
Evolutionary origin and functional diversification of …
Aminotransferases (ATs) are pyridoxal 5′-phosphate–dependent enzymes that catalyze the transamination reactions between amino acid donor and keto acid acceptor substrates. Modern AT enzymes constitute ∼2% of all classified enzymatic activities, play central roles in nitrogen metabolism, and generate multitude of primary and secondary metabolites.
Aminotransferases - Clinical Methods - NCBI Bookshelf
Aminotransferases or transaminases are a group of enzymes that catalyze the interconversion of amino acids and oxoacids by transfer of amino groups. Aspartate aminotransferase (AST), formerly termed glutamate oxaloacetate transaminase (GOT), and alanine aminotransferase (ALT), formerly termed glutamate pyruvate transaminase (GPT), are the two ...
Transaminase | Amino Acid, Metabolism, Liver | Britannica
Transaminase, any of a group of enzymes that catalyze the transfer of the amino group (―NH2) of an amino acid to a carbonyl compound, commonly an a-keto acid (an acid with the general formula RCOCOOH). The liver, for example, contains specific transaminases for the transfer of an amino group from
Transamination – Definition, Mechanism, Importance, & Diagram
2023年8月29日 · Transamination is a biochemical process that involves the transfer of an amino group (NH 2) from one amino acid (except lysine, proline, and threonine) to a keto acid (without an amine group), producing a new amino acid and a corresponding new keto acid. It is thus a reversible amination and deamination.