Alkannin - Wikipedia
Alkannin is a natural dye that is obtained from the extracts of the plant dyer's alkanet (Alkanna tinctoria) which is found in the Mediterranean region. The dye is used as a food coloring and in cosmetics; within the European E number schedule, it is numbered E103 .
Alkannin (左旋紫草素) - 仅供科研 | 凋亡诱导剂 | MCE
(-)-Alkannin, found in Alkanna tinctoria, is used as a food coloring. (-)-Alkannin shows anticancer activity, arrests cell cycle, and induces apoptosis. (-)-Alkannin improves hepatic inflammation in a Rho-kinase pathway.
Alkannin | C16H16O5 | CID 72521 - PubChem
Alkannin | C16H16O5 | CID 72521 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Alkannin | Elk3抑制剂 - MCE
Alkannin is a potent and specific inhibitor to PKM2, an enzyme that dictates the last rate-limiting step of glycolysis, which is essential for cancer cells’ proliferation and survival. In the absence of D-fructose-1,6-bisphosphate (FBP), the IC 50 of Alkannin is 0.3 μM.
Pharmacological and analytical aspects of alkannin/shikonin and …
2022年10月1日 · Alkannin and shikonin (A/S) are enantiomeric pair and naphthoquinone pigments (Boulos, Rahama, Hegazy, & Efferth, 2019) which are well known for their therapeutic, cosmetic and coloring applications (Fig. 1). Plants containing these bioactive pigments are traditionally used for curing various ailments since centuries.
Alkannin - an overview | ScienceDirect Topics
Alkannin is an antioxidant and has an antimicrobial effect against Straphylococcus aureus and S. epidermis. It is also known to have wound healing, antitumor, and antithrombotic properties.
Alkannin - an overview | ScienceDirect Topics
2010年6月2日 · Shikonin and its stereoisomer, alkanin, (Fig. 3) are the water-insoluble pigments and naturally occurring isohexenylnaphthazarins which are abundantly found in the roots of plants belong to the Boraginaceae family including Alkanna tinctoria (Alkanet, Alkanna), Arnebia euchroma and Lithospermum erythrorhizon (Lithospermum).
抗肿瘤紫草素/alkannin衍生物的最新进展：以结构分类、合成方法 …
新紫草素衍生物的设计、合成和开发不断进行，旨在通过增加对癌细胞的细胞毒性和同时降低对正常细胞的毒性来提高治疗效果。 尽管近年来紫草素衍生物的开发取得了重大进展，并发表了一些这方面的综述，但其结构分类、合成方法、以及这些化合物的抗肿瘤作用机制的多样性尚未得到充分考虑。 本综述旨在通过回顾过去二十年（从 2000 年至今）进行的研究，提供这方面的综合数据。 紫草素及其对映体类似物 alkaninn 是药物发现和抗癌剂开发中普遍存在的天然先导化合物。 …
Role of Alkannin in the Therapeutic Targeting of Protein-Tyrosine ...
2024年8月18日 · Alkannin is a plant-derived naphthoquinone that is isolated from the Boraginaceae family plants. In our previous studies, we found that shikonin, which is the R -enantiomer of alkannin, has potent antidiabetic activity by inhibiting the action of the aldose reductase (AR) enzyme and the protei …
Advance in Anti-tumor Mechanisms of Shikonin, Alkannin and …
Shikonin, alkannin and their derivatives, the main ingredient of Lithospermum erythrorhizon and Arnebia euchroma (Royle) Johnst native to Inner Mongolian and Northwest of China respectively, hold promising potentials for antitumor effects via multiple-target mechanisms.
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