Benzoxazole - Wikipedia
Benzoxazole is an aromatic organic compound with a molecular formula C 7 H 5 NO, a benzene -fused oxazole ring structure, and an odor similar to pyridine. [1][2] Although benzoxazole itself is of little practical value, many derivatives of benzoxazoles are commercially important.
阿苯达唑 - 百度百科
阿苯达唑为一高效低毒的广谱驱虫药，临床可用于驱蛔虫、蛲虫、绦虫、鞭虫、钩虫、粪圆线虫等。 在体内代谢为亚砜类或砜类后，抑制寄生虫对葡萄糖的吸收，导致虫体糖原耗竭，或抑制延胡索酸还原酶系统，阻碍ATP的产生，使寄生虫无法存活和繁殖。 主要用作高效广谱驱虫药，系苯并咪唑类药物中驱虫谱较广、杀虫作用最强的一种。 适用于驱除蛔虫、蛲虫、钩虫、鞭虫，治疗各种类型的囊虫病，也可用于家畜的驱虫。 本品为5- (丙硫基-1H-苯并咪唑-2-基)氨基甲酸甲酯，按 …
苯并恶唑 - 百度百科
出示此化学品安全技术说明书给到现场的医生看。 1. 用水雾、干粉、泡沫或二氧化碳灭火剂灭火。 2. 避免使用直流水灭火，直流水可能导致可燃性液体的飞溅，使火势扩散。 1. 消防人员须佩戴携气式呼吸器，穿全身消防服，在上风向灭火。 2. 尽可能将容器从火场移至空旷处。 3. 处在火场中的容器若已变色或从安全泄压装置中发出声音，必须马上撤离。 4. 隔离事故现场，禁止无关人员进入。 收容和处理消防水，防止污染环境。 1.
Benzoxazoles | C7H5NO | CID 9228 - PubChem
Benzoxazole | C7H5NO | CID 9228 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Benzoxazoles - an overview | ScienceDirect Topics
Benzoxazole is an important class of heterocycle having a bicyclic structure in which an aryl ring is fused with the “d” site of an oxazole moiety. You might find these chapters and articles relevant to this topic. Thomas F. DeRosa, in Advances in Synthetic Organic Chemistry and Methods Reported in US Patents, 2006.
Targeting disease with benzoxazoles: a comprehensive review
2024年2月18日 · Benzoxazole is an attractive scaffold in medicinal chemistry due to its diverse biological applications. From 2016 to 2023, a plethora of benzoxazole derivatives have been synthesized and evaluated for their pharmacological activities but a …
Design, Synthesis, and Activity Evaluation of Novel Benzazole ...
2024年6月18日 · In this study, three series of benzazole compounds were designed as dual-target (PD-L1/CYP51) inhibitors using the skeleton splicing approach; their molecular structures were synthesized and evaluated accordingly. Among them, the compounds 9a-2, 12a-2, and 12b-1 exhibited potent antifungal activity and dual-target inhibition ability.
Antibacterial activity and mechanism of action of the benzazole ...
2017年8月18日 · Benzimidazoles and benzothiazoles are important pharmacophores in medicinal chemistry owing to their involvement as key components for various biological activities. Benzothiazoles and their derivatives exhibit antitumor [2], antimicrobial [3], …
Benzoxazole derivatives: design, synthesis and biological …
2018年8月12日 · Prompted by the above findings (Fig. 2) in the present study, we hereby report the synthesis, antimicrobial and anticancer activities of a series of benzoxazole derivatives. Marketed drugs containing benzoxazole. Design of benzoxazole molecules for antimicrobial and anticancer potential based on literature.
Importance of Fluorine in Benzazole Compounds - PMC
2020年10月14日 · In medicinal chemistry, the incorporation of fluorine in small molecules imparts a significant enhancement their biological activities compared to non-fluorinated molecules. In this short review, we will highlight the importance of incorporating fluorine as a basic appendage in benzothiazole and benzimidazole skeletons.
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