蛋白质的脂化修饰 - 知乎 - 知乎专栏
2020年9月17日 · 蛋白质的脂化（lipidation）修饰是指脂类分子与蛋白质共价结合，从而改变其结构与功能。 很多人将脂化修饰看作一种翻译后修饰（PTM），其实有些脂修饰可以是共翻译过程，如NMT催化的豆蔻酰化等。
Protein lipidation in health and disease: molecular basis ...
2024年3月15日 · In this review, we discuss the known regulatory enzymes and catalytic mechanisms of various lipidation types, outline the role of protein lipidation in physiology and disease, and highlight ...
Protein lipidation: Occurrence, mechanisms, biological functions, …
Protein lipidation, including cysteine prenylation, N-terminal glycine myristoylation, cysteine palmitoylation, and serine and lysine fatty acylation, occurs in many proteins in eukaryotic cells and regulates numerous biological pathways, such as membrane trafficking, protein secretion, signal transduction, and apoptosis.
Protein lipidation in cell signaling and diseases: function, regulation ...
Protein lipidation is a unique co-translational or posttranslational modification that plays a critical role in cell signaling, and dynamically regulates protein functions in response to extrinsic and intrinsic cues.
The Biosynthesis and Applications of Protein Lipidation
2024年10月23日 · Protein lipidation dramatically affects protein structure, localization, and trafficking via remodeling protein–membrane and protein–protein interactions through hydrophobic lipid moieties. Understanding the biosynthesis of lipidated proteins, whether natural ones or mimetics, is crucial for reconstructing, validating, and studying the ...
脂质化- 生物百科 - 生物行
脂质化（lipidation）是指在蛋白质或其他分子上共价附着脂质基团的一种翻译后修饰。 脂质化在细胞膜锚定、信号传导、蛋白质相互作用和膜蛋白的稳定性中发挥重要作用。
蛋白质的脂化修饰 - 哔哩哔哩
2020年9月18日 · 蛋白质的脂化（lipidation）修饰是指脂类分子与蛋白质共价结合，从而改变其结构与功能。 很多人将脂化修饰看作一种翻译后修饰（PTM），其实有些脂修饰可以是共翻译过程，如NMT催化的豆蔻酰化等。
Protein Lipidation in Cell Signaling and Diseases ... - ScienceDirect
2018年7月19日 · Lipidation modulates the function of targeted proteins by increasing their binding affinity to biological membranes, rapidly switching their subcellular localizations, affecting folding and stability, and modulating association with other proteins.
Editorial: Protein lipidation in health and disease - Frontiers
Protein lipidation, the attachment of lipids to proteins, influences how proteins fold, their stability, trafficking, interaction with other proteins, and association with specific domains on cellular membranes.
Protein Lipidation: Occurrence, Mechanisms, Biological Functions, …
2018年1月2日 · Protein lipidation, including cysteine prenylation, N-terminal glycine myristoylation, cysteine palmitoylation, and serine and lysine fatty acylation, occurs in many proteins in eukaryotic cells and regulates numerous biological pathways, such as membrane trafficking, protein secretion, signal transduction, and apoptosis.